Liquid Chromatography-Triple Quadrupole Mass Spectrometer (LC-MS/MS)

Liquid Chromatography-Triple Quadrupole Mass Spectrometer (LC-MS/MS)

Make: Shimadzu

Model: LCMS 8045RX

  • API-ESI (Atmospheric Pressure Ionization – Electrospray Ionization) Techniques
  • PDA Detector range: 200-800nm
  • Ultra-Fast Mass Spectrometry (UFMS) for rapid analysis, quick polarity switching and stable signal detection
  • Mass Range : m/z 2 to 2,000
  • Resolution : R < 0.7 u FWHM and adjustable to 0.5 u
  • Scan speed : Max. 30,000 u/sec (in all scan modes) (0.1 u step: 300,000 data points/sec)
  • Positive-negative ion polarity switching time : 5 msec
  • MRM transition speed : Max. 555 channels/sec
  • Mass Stability : 0.05 Da/24 hr
  • Quantification at ppb level in MRM method

LC-MS/MS is used in various fields such as

  • Pharmaceutical Industry – Drug testing, Contamination analysis
  • Food Industry – Food Quality Assessment.
  • Environmental Application – Soil and Water Pollution Analysis
  • LC-MS/MS is also used in metabolomics, proteomics, and genomics studies, as well as in the analysis of natural products and biofuels.
  • LCMS is applied in many industries such as pharmaceuticals, biopharmaceuticals, forensic, industrial, food and environmental sector
  • For clinical research, the analysis of drugs, vitamins and minerals in whole blood, plasma, serum and urine
EQUIPMENT_NAME UG /PG Students from Academic Institution (in INR) Research Scholar from Academic Institution (in INR) Project Staff from Academic Institution (in INR) Faculty Members from Academic Institution (in INR) Research Scientist from R&D Organizations (in INR) Industry Personnel from Industry (in INR) Personnel from Non – Government Organization (in INR)
LC-DAD 1200 1200 1200 1200 2000 2000 2000
LC-DAD-MS 2000 2000 2000 2000 3000 3000 3000
LC-MS-Qualitative/Scan/ SIM_(ESI-Positive) 1800 1800 1800 1800 2400 2400 2400
LC-MS-Qualitative/Scan/ SIM_(ESI-Negative) 1800 1800 1800 1800 2400 2400 2400
LC-MSMS or MRM per mass(m/z)_ESI-Positive 1000 1000 1000 1000 1800 1800 1800
LC-MSMS or MRM per mass(m/z)_ESI-Negative 1000 1000 1000 1000 1800 1800 1800
LC-MSMS-Quantitative/Analyte 2500 2500 2500 2500 3500 3500 3500
LC-MSMS-Quantitative/Analyte with Method Development 3500 3500 3500 3500 5000 5000 5000

PRP 417
Pearl Research Park
Centre for Nanobiotechnology

Dr. John Thomas
Associate Professor
Centre for Nanobiotechnology
VIT, Vellore-632014
Facility E-mail ID: cnbt.lcmsms@vit.ac.in
Phone: 0416 220 4216